Sue-Hwa Lin Selected Research

osteoblast cadherin

12/2015	Cadherin-11 endocytosis through binding to clathrin promotes cadherin-11-mediated migration in prostate cancer cells.
3/2015	Angiomotin is a novel component of cadherin-11/β-catenin/p120 complex and is critical for cadherin-11-mediated cell migration.
1/2014	Cadherin-11 in renal cell carcinoma bone metastasis.
11/2013	Inhibition of cell adhesion by a cadherin-11 antibody thwarts bone metastasis.
6/2010	Cadherin-11 increases migration and invasion of prostate cancer cells and enhances their interaction with osteoblasts.
5/2010	Androgen depletion up-regulates cadherin-11 expression in prostate cancer.
10/2008	Expression of the extracellular domain of OB-cadherin as an Fc fusion protein using bicistronic retroviral expression vector.
8/2008	Cadherin-11 promotes the metastasis of prostate cancer cells to bone.

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Sue-Hwa Lin Research Topics

Disease

55	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 08/2002
48	Neoplasms (Cancer) 01/2022 - 03/2002
38	Neoplasm Metastasis (Metastasis) 01/2022 - 05/2002
9	Carcinogenesis 01/2020 - 04/2004
6	Carcinoma (Carcinomatosis) 01/2020 - 05/2002
5	Renal Cell Carcinoma (Grawitz Tumor) 01/2020 - 07/2002
4	Breast Neoplasms (Breast Cancer) 01/2017 - 05/2004
2	Disease Progression 01/2020 - 01/2015
2	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 10/2018 - 12/2016
2	Lymphatic Metastasis 04/2013 - 01/2007
2	Ovarian Neoplasms (Ovarian Cancer) 08/2010 - 06/2010
1	Myositis Ossificans (Fibrodysplasia Ossificans Progressiva) 01/2022
1	Heterotopic Ossification (Ectopic Ossification) 01/2022
1	Diarrhea 01/2020
1	Hypertension (High Blood Pressure) 01/2020
1	Osteolysis 01/2020
1	Seminoma 01/2018
1	Neurofibromatosis 2 (Neurofibromatosis Type II) 02/2017
1	Feminization 01/2017
1	Residual Neoplasm 12/2016
1	Teratoma (Teratoid Tumor) 12/2016
1	Adenoma (Adenomas) 01/2016

Drug/Important Bio-Agent (IBA)

19	Proteins (Proteins, Gene)FDA Link 10/2021 - 07/2002
14	AndrogensIBA 01/2021 - 05/2002
8	osteoblast cadherinIBA 12/2015 - 08/2008
6	cabozantinibIBA 01/2020 - 11/2015
6	Androgen Receptors (Androgen Receptor)IBA 01/2020 - 03/2002
6	Biomarkers (Surrogate Marker)IBA 01/2020 - 02/2012
6	CEACAM1 ProteinIBA 11/2006 - 03/2002
5	Protein Isoforms (Isoforms)IBA 01/2022 - 06/2004
5	Conditioned Culture MediaIBA 01/2018 - 09/2002
5	Pharmaceutical PreparationsIBA 01/2018 - 04/2004
5	Biological ProductsIBA 10/2014 - 05/2002
4	Hormones (Hormone)IBA 01/2020 - 08/2003
4	Cell Adhesion MoleculesIBA 12/2015 - 09/2002
3	Radium-223IBA 01/2021 - 12/2018
3	Cadherins (E-Cadherin)IBA 03/2015 - 11/2013
3	Small Interfering RNA (siRNA)IBA 08/2010 - 09/2005
3	RadiopharmaceuticalsIBA 05/2010 - 11/2005
2	Bone Morphogenetic Protein 4IBA 01/2022 - 01/2021
2	Radioisotopes (Radionuclides)IBA 01/2021 - 05/2010
2	Steroid Receptors (Steroid Receptor)IBA 01/2020 - 09/2005
2	CytokinesIBA 01/2020 - 11/2006
2	Phosphotransferases (Kinase)IBA 01/2018 - 07/2015
2	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 09/2017 - 11/2015
2	Estrogen ReceptorsIBA 01/2017 - 01/2008
2	Estrogens (Estrogen)FDA Link 01/2017 - 01/2008
2	IntegrinsIBA 11/2015 - 04/2013
2	LigandsIBA 03/2015 - 12/2014
2	DNA (Deoxyribonucleic Acid)IBA 12/2014 - 08/2010
2	LuciferasesIBA 01/2013 - 09/2002
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2012 - 07/2007
2	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 07/2010 - 01/2008
2	Docetaxel (Taxotere)FDA Link 06/2008 - 03/2008
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2008 - 09/2002
2	Thalidomide (Thalomid)FDA Link 03/2008 - 08/2006
2	Transcription Factors (Transcription Factor)IBA 01/2008 - 05/2004
2	ProlactinIBA 01/2007 - 01/2003
2	Zoledronic Acid (Zometa)FDA Link 08/2006 - 08/2003
2	Bromodeoxyuridine (BrdU)IBA 09/2005 - 03/2002
1	PalovaroteneIBA 01/2022
1	TenascinIBA 01/2022
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2022
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 01/2022
1	Proline (L-Proline)FDA Link 10/2021
1	Alanine (L-Alanine)FDA Link 10/2021
1	CateninsIBA 04/2021
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2021
1	MopidamolIBA 01/2021
1	LumicanIBA 01/2020
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2020
1	GlucocorticoidsIBA 01/2020
1	HydrogelsIBA 01/2020
1	FucosyltransferasesIBA 01/2019
1	E-SelectinIBA 01/2019
1	GlypicansIBA 10/2018
1	Cisplatin (Platino)FDA LinkGeneric 10/2018
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2018
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 01/2018
1	CalciumIBA 01/2018
1	Calcium-Calmodulin-Dependent Protein KinasesIBA 01/2018
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 01/2018
1	TensinsIBA 01/2018
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018
1	human ERBB2 proteinIBA 01/2018
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2018
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2018
1	Alkaline PhosphataseIBA 09/2017
1	sipuleucel-T (APC8015)FDA Link 09/2017
1	AngiomotinsIBA 02/2017
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2017
1	NucleotidesIBA 01/2016
1	Transforming Growth Factor-beta Type I ReceptorIBA 01/2016

Therapy/Procedure

32	Therapeutics 01/2022 - 05/2002
7	Castration 01/2021 - 07/2007
5	Drug Therapy (Chemotherapy) 01/2021 - 11/2005
2	Prostatectomy (Retropubic Prostatectomy) 12/2019 - 01/2018
1	Drug Tapering 01/2020
1	Immunotherapy 09/2017
1	Mastectomy (Mammectomy) 01/2017